Anatomic Pathology

Building on the foundation of the past, the Institute of Pathology fast-tracked its modernization in several directions. Initially, the Institute established the most comprehensive library of monoclonal antibodies for Immunohistochemistry and has become the referral center for difficult Surgical Pathology cases. The Institute of Pathology was the first to automate Immunohistochemistry with the state-of-the-art Biogenex 600. Autocyte liquid-based automated pap smear technology also put the institute in the forefront of cervical cancer screening. The Histopathology section is the most advanced in the country with its sophisticated and automated Slide Strainer, Tissue Processors, Tissue Cryostat, and a Surgical Pathology Cutting Station. Another recent first in the field of Anatomic Pathology was the introduction of Chromogenic In-Situ-Hybridization (CISH) for HER-2 as a guide to treatment of advanced breast cancer with Herceptin.

The Anatomic Pathology Section offers:

Histopathology

1. Routine Histopathological Examination
2. Fine Needle Aspiration Biopsy
3. Papanicolau Smear
4. Cytopathological Services
* Cell Block and Cytology
* Cytospin
5. Frozen Section
6. Renal Biopsy
* Light Microscopy
* Immunofluorescence
* Electron Microscopy
7. Skin Biopsy
* Light Microscopy
* Immunofluorescence
8. Muscle Biopsy
* Histochemical Staining
* Dystrophin Immunohistochemistry
* Electron Miscroscopy
9. Breast Panel
* Estrogen Receptor Assay
* Progesterone Receptor Assay
* C-erb-2 (Her2-neu)
* p-53
* DNA Ploidy Analysis
10. Nerve Biopsy with Electron Microscopy
11. Slide Review
12. Slide Processing
13. Special Stains (Histochemistry)
* Alcian Blue
* Amyloid stain (Congo Red)
* Bielschowsky’s Method for Axis Cylinder and Dendrites
* Fite Faraco (AFB)
* Gomoris Method for Reticulum
* Trichrome (Masson’s)
* Mucicarmine (Mayers)
* Oil Red O
* Periodic Acid Schiff (PAS)
* Perl’s Method for Iron
* Reticulin Stain
* Silver Stain
* Kluver-Barrera for Myelin and Nerve Cells
* Weigert’s Method for Elastic Fibers
* Zimmerman Method for Nerve Cells and Fiber
* Tissue Giemsa (H. Pylori)
14. Immunohistochemical Staining
*Actin
* Adrenocorticotropic Hormone (ACTH)
* ALK
* Alpha Feto Protein (AFP)
* Alpha-1 Antichymotrypsin (AACT)
* Bcl-x
* Bcl-2
* Bcl-6
* BRCA-1 protein
* Breast Carcinoma
* Cero B4
* Calretinin
* C-erb-2
* CA 125
* CA 15-3
* CA 19-9
* Calcitonin
* Carcinoembryonic Antigen (CEA)
* Cathepsin D
* CD 3
* CD 4
* CD 8
* CD 15
* CD 20
* CD 30
* CD 31
* CD 34
* CD 45R
* CD 45RO
* CD 99
* CD 57
* CD 79a
* CD 1A
* CEA-Polyclonal
* Chromogranin
* Collagen IV
* Cyclin D1
* Cytokeratin (HMW)
* Cytokeratin 5 & 6
* Cytokeratin 7
* Cytokeratin 18
* Cytokeratin 20
* Cytomegalovirus
* Cytokeratin
* Desmin
* E. Cadherin
* EGFR
* Epithelial Specific Antigen (ESA)
* Estradiol
* Factor VIII
* Follicle Stimulating Hormone (FSH)
* GFAP
* Gastrin
* Glucagon
* Growth Hormone
* Human Chorionic Gonadotrophin
* IgA
* IgD
* IgG
* IgM
* Insulin
* Kappa
* Ki-67
* LCA
* Lambda
* Leutinizing Hormone (LH)
* Lysozyme
* Melan A
* Melanoma
* Myeloid Specific
* Myoglobin
* Neurofilament Protein
* Neuron Specific Enolase
* Osteorectin
* Osteocalcin
* P63
* P-53
* PCNA
* PDGF
* Placental Alkaline Phosphatase
* P504 S
* Placental Lactogen
* Pneumocystis Carinii
* Prolactin
* Prostate Specific Antigen
* Prostatic Acid Phosphatase
* Pituitary Hormones Panel
* S-100
* Sarcomeric Actin
* Small Cell Lung Cancer (SCLC)
* Smooth Muscle Actin
* Somatostatin
* Synaptophysin
* TdT
* Thyroglobulin
* Thyroid Stimulating Hormone (TSH)
* Villin
* Vimentin
* Hepatocyte Specific Antigen
* Myeloperoxidase
* Inhibin
* H. Pylori
* CD 117 (C-KIT)
* TTF-1
* CD 99
* Chromogenic In-Situ Hybridization (CISH)
* Cytokeratin 8
* Fascin
* Smooth Muscle Myosin (Heavy Chain)
* Caldesmon
* CD10
15. Post-Mortem Examination
* Medico Legal
* Non-Medico Legal
16. Immunohistochemistry
17. Cytopathology
18. Renal Pathology
19. Breast Cancer Profile
20. Chromogenic In-Situ Hybridization for HER-2 (neu)